Bioactive compounds and antifungal activity of three different seaweed species Ulva lactuca,Sargassum tenerrimum and Laurencia obtusa collected from Okha coast,Western India

作     者：Megha Barot Nirmal Kumar JI Rita NKumar 

作者机构：P.G.Department of Environmental Science and TechnologyInstitute of Science and Technology for Advanced Studies and ResearchVallabh Vidyanagar-388120GujaratIndia 

出 版 物：《Journal of Coastal Life Medicine》 (海岸生命医学杂志（英文版）)

年 卷 期：2016年第4卷第4期

页      面：284-289页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Supported by University Grant Commission(UGC-F No.42-415) New Delhi India 

主　　题：Antifungal activity Bioactive compounds Crude extract Gas chromatography-mass spectrometer Seaweeds 

摘      要：Objective:To evaluate bioactive compounds responsible for antifungal activity from seaweeds of Okha coast,Western ***:Each species were extracted with different solvents with increasing polarity:hexane,ethyl acetate,chloroform and methanol using Soxhlet *** antifungal activity was determined by agar diffusion plate method by using fluconazole,ketoconazole and amphotericin B as *** chromatography-mass spectrometer analysis was done for identification of bioactive compounds present in crude ***:The gas chromatography-mass spectrometer analysis of all the extracts revealed the presence of steroids,fatty acids and esters *** the three species,the maximum crude extract yield(53.46%)and the largest inhibition zone(36 mm)were recorded in methanol extract of Ulva lactuca,whereas the minimum crude extract yield and inhibition zone were recorded in chloroform extract of the same species as 0.5%and 10 mm,*** and ethyl acetate extract showed the maximum antifungal activity and the major important compounds like steroids,fatty acids and esters were detected with higher amount in all the ***:The present study revealed that the different seaweed extracts showed moderate to significant antifungal activity against the strains tested as compared with the standard fungicides,and polar solvents methanol and ethyl acetate were comparatively efficient for extraction of different metabolites that are responsible for antifungal activity.