Responses of Patients with Disorders of Consciousness to Habit Stimulation:A Quantitative EEG Study

作     者：Jingqi Li Jiamin Shen Shiqin Liu Maelig Chauvel Wenwei Yang Jian Mei Ling Lei Li Wu Jian Gao Yong Yang 

作者机构：Ming Zhou Nao Kang Rehabilitation HospitalHangzhou 310000China College of Life Information Science and Instrument EngineeringHangzhou Dianzi UniversityHangzhou 310018China Paris Descartes University45 Rue des Saints-Peres75006 ParisFrance Rehabilitation CenterWu Jing HospitalHangzhou 310051China 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2018年第34卷第4期

页      面：691-699页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(81671038) 

主　　题：EEG Disorder of consciousness Habitstimulation Wavelet transformation Nonlinear dynamics Differential analysis 

摘      要：Whether habit stimulation is effective in DOC patient arousal has not been reported. In this paper, we analyzed the responses of DOC patients to habit stimulation. Nineteen DOC patients with alcohol consumption or smoking habits were recruited and 64-channel EEG signals were acquired both at the resting state and at three stimulation states. Wavelet transformation and nonlinear dynamics were used to extract the features of EEG signals and four brain lobes were selected to investigate the degree of EEG response to habit stimulation. Results showed that the highest degree of EEG response was from the callname stimulation, followed by habit and music stimulations. Significant differences in EEG wavelet energy and response coefficient were found both between habit and music stimulation, and between habit and call-name stimulation. These findings prove that habit stimulation induces relatively more intense EEG responses in DOC patients than music stimulation, suggesting that it may be a relevant additional method for eliciting patient arousal.