Diagnostic algorithms in autoimmune encephalitis

作     者：Valentina Damato 

作者机构：Institute of NeurologyCatholic University of Sacred Heart00168 RomeItaly 

出 版 物：《Neuroimmunology and Neuroinflammation》 (神经免疫与神经炎症（英文版）)

年 卷 期：2016年第3卷第1期

页      面：93-97页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Autoimmune encephalitis neuronal surface autoantibodies paraneoplastic syndromes 

摘      要：Over the past decade the discovery of novel forms of encephalitis associated with neuronal surface antibodies had changed the paradigms for diagnosing and treating disorders that were previously *** of clinical syndromes,consistent methods of diagnosis,and early targeted immunotherapy can lead to a favorable outcome in diseases that may be associated with significant disability or death if left *** the conditions associated with neuronal surface antibodies are briefly reviewed,some general aspects of these syndromes are considered and guidelines that could help in the recognition of these disorders are ***,a diagnostic algorithm to detect and characterize neuronal cell surface autoantibodies is suggested and some of the caveats of serum testing are *** directions will involve the identification of novel autoantibodies,the standardization of methods to detect and characterize them,as well as evaluation of the most efficacious therapeutic strategies in patients with established diagnosis of autoimmune encephalitis.