Hepatic Encephalopathy: An Update on the Pathophysiology and Therapeutic Options

作     者：Saleh Elwir Robert S.Rahimi 

作者机构：Annette C.and Harold C.Simmons Transplant Institute Baylor University Medical Center Dallas TX USA 

出 版 物：《Journal of Clinical and Translational Hepatology》 (临床与转化肝病杂志（英文版）)

年 卷 期：2017年第5卷第2期

页      面：142-151页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Ocera Therapeutics 

主　　题：Hepatic encephalopathy Cirrhosis Lactulose Rifaximin 

摘      要：Hepatic encephalopathy is a spectrum of reversible neuropsychiatric abnormalities,seen in patients with liver dysfunction and/or portosystemic *** of the most debilitating complications of cirrhosis,encephalopathy affects 30-45% of *** addition to significantly affecting the lives of patients and their caregivers,it is also associated with increased morbidity and mortality as well as significant utilization of health care *** this paper,we provide an overview on the pathophysiology,diagnosis,management and newer therapies of hepatic encephalopathy.