Epidural spinal cord compression as initial clinical presentation of an acute myeloid leukaemia: case report and literature review

作     者：Dominique N'Dri Oka Alpha Boubacar Bah André Valentin Tokpa Louis Derou 

作者机构：Department of Neurosurgery Teaching Hospital of Yopougon in Abidjan Ivory Coast 21 BP 632 Abidjan C(o)te d'lvoire Department of NeurosurgeryTeaching Hospital of Conakry Conakry Guinea 

出 版 物：《Chinese Neurosurgical Journal》 (中华神经外科杂志（英文）)

年 卷 期：2016年第2卷第1期

页      面：-页

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100214[医学-肿瘤学] 10[医学] 1009[医学-特种医学] 

主　　题：Spinal cord compression Initial epidural localization Acute myeloid leukaemia 

摘      要：Epidural localization of myeloid leukaemia is rarely reported. Spinal cord compression as an initial presentation of acute myeloid leukaemia is extremely rare. This is a report of a 17-year-old black boy who presented to emergency department with neurological symptoms of spinal cord compression. Imaging modalities showed multiple soft tissue masses in the epidural space. After surgical treatment, histopathological examination of the epidural mass showed myeloid leukaemia cells infiltration. Literature review on Medline and “scholar Google database was done. The characteristics and management of extra-medullary leukaemia are discussed. Granulocytic sarcoma, myeloid sarcoma or chloroma with acute myeloid leukaemia should be considered as part of epidural spinal cord compression. Therefore surgery is indicated on an emergent basis.