Effect of aqueous extract of Murraya koenigii on haematological,hormonal and lipid profile of Albino rats

作     者：Sushmita Choudhury Manoranjan Prasad Sinha 

作者机构：Department of ZoologyRanchi UniversityRanchi 834008India 

出 版 物：《Journal of Coastal Life Medicine》 (海岸生命医学杂志（英文版）)

年 卷 期：2015年第11期

页      面：901-905页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Supported by SERB New Delhi(SB/FT/LS-406/2012)under the Fast Track Scheme for Young Scientist 

主　　题：Murraya koenigii Haematological Hormonal Serum lipid 

摘      要：Objective:To investigate the effect of aqueous extract of Murraya koenigii leaves on some haematological,hormonal and serum lipid parameters in ***:We evaluated whether oral administration of Murraya koenigii affected the haematological,hormonal and lipid *** 7 days of oral administration of 250 mg/kg and 500 mg/kg body weight,other profiles were ***:The results showed that the extract administered significantly increased(P0.05)packed cell volume,haemoglobin concentration,red blood cell,mean corpuscular hemoglobin,mean corpuscular hemoglobin concentration,mean corpuscular volume and decreased the platelet count(P0.05)at the dose of 250 mg/kg and 500 mg/kg body weight when compared with *** extract significantly increased(P0.05)white blood cell count at all doses administered when compared with *** showed that thyronine and thyroxine were increased,while thyroid stimulating hormone was decreased significantly(P0.05)at high doses *** recorded data in the present study showed that the testosterone value was reduced significantly(P0.05)from control *** the extract significantly reduced(P0.05)the total cholesterol concentration and low density lipoproteins cholesterol concentration in the serum while it had no significant effect on serum high density lipoprotein cholesterol concentration at all doses ***:This study suggests that the extracts may have beneficial effect on serum cholesterol concentration,can act as a stimulant to thyroid functions as well as in anemia and immunity dependent disorders and also as a potent contraceptive.