Effects of root,shoot,leaf and seed extracts of seven Artemisia species on HIV-1 replication and CD4 expression
Effects of root, shoot, leaf and seed extracts of sevenArtemisia species on HIV-1 replication and CD4 expression作者机构：Department of BiotechnologyFaculty of Advanced Sciences and TechnologiesUniversity of IsfahanIsfahan 81746-73441Iran Faculty of ScienceUniversity of IsfahanIsfahan 81746-73441Iran
出 版 物：《Journal of Coastal Life Medicine》 (海岸生命医学杂志（英文版）)
年 卷 期：2015年第12期
页 面：996-999页
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
基 金：Supported by the grant(91/82779)from the University of Isfahan Iran
主 题：Artemisia HIV-1 CD4 PBMC Antiviral activity
摘 要：Objective:To investigate the effects of flower,leaf,shoot and root extracts of seven Artemisia species on peripheral blood mononuclear cells(PBMCs)toxicity and HIV-1 ***:The studied Artemisia species were Artemisia absinthium,Artemisia khorasanica,Artemisia deserti,Artemisia fragrans,Artemisia aucheri,Artemisia sieberi and Artemisia *** activity of these plant extracts on HIV-1 replication and CD4 expression was performed by HIV-1 p24 antigen kit and flow cytometry ***:The results demonstrated that flower extracts of all species increased PBMCs number more than shoot,leaf and root ***,the frequency of CD4 expression in PBMC was not increased in the presence of all flower *** flower extracts of all species had inhibitory effect on HIV-1 ***:In conclusion,the results demonstrated that flower extracts of Artemisia species are good candidates for further studies as anticancer agents.
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