Alcohol and tea consumption in relation to the risk ofnasopharyngeal carcinoma in Guangdong, China

作     者：Hong-Lian RUAN Feng-Hua XU Wen-Sheng LIU Qi-Sheng FENG Li-Zhen CHEN Yi-Xin ZENG Wei-Hua JIA 

作者机构：State Key Laboratory of Oncology in Southern ChinaGuangzhou 510060China School of Public HealthSun Yat-Sen UniversityGuangzhou 510080China Department of Experiment ResearchSun Yat-sen UniversityCancer CenterGuangzhou 510060China 

出 版 物：《Frontiers of Medicine》 (医学前沿（英文版）)

年 卷 期：2010年第4卷第4期

页      面：448-456页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.30671798 and 30471487) the National Science and Technology Support Program of China(No.2006BAI02A11) the National Major Basic Research Program of China(863 Program)(No.2006AA02A404) 

主　　题：nasopharyngeal carcinoma case-control study alcohol consumption tea consumption 

摘      要：To investigate whether alcohol and tea con-sumption has an etiological association with nasophar-yngeal carcinoma(NPC)in a high-incident population,a large scale case-control study was *** study included 2846 individuals in Guangdong Province,China,with 1387 newly diagnosed cases of NPC and 1459 frequency-matched *** histories of alcohol and tea consumption were obtained via personal *** regarding socio-demographic charac-teristics(age,sex,education,dialect and household type),family history of NPC,Epstein-Barr virus(EBV)infection,dietary habits and other potential confounding factors was also *** analysis was performed using uncondi-tional logistic regression to calculate odds ratios(OR)and 95%confidence intervals(CI).The risk of NPC was found to be associated with habitual alcohol consumption and tea *** consumption has been associated with a decreased occurrence of NPC(OR=0.62),while con-sumption of alcohol was associated with a complex ***fically,moderate consumption of alcohol was associated with decreased risk of NPC,while overuse,especially strong distillate spirits,appeared to be a risk factor.