Recognition of amino acids and anions by a Zn(Ⅱ)-methylazacalix[4]pyridine complex

作     者：GONG HanYuan, WANG DeXian, HUANG ZhiTang & WANG MeiXiang Beijing National Laboratory for Molecular Sciences, CAS Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China 

作者机构：Beijing National Laboratory for Molecular Sciences CAS Laboratory of Molecular Recognition and Function Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2009年第52卷第10期

页      面：1639-1645页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Supported by the National Natural Science Foundation of China (Grant No. 20672115, 20875094 & 20532030) Ministry of Science and Technology of China (Grant No. 2007CB808005) and the Chinese Academy of Sciences 

主　　题：Zn(Ⅱ)-MACP-4 complex amino acids anions recognition 

摘      要：As a powerful macrocyclic host molecule with unique conformation and cavity structure that are fine-tuned by the bridging nitrogen atoms, methylazacalix[4]pyridine (MACP-4) has been shown to selectively recognize Zn2+ and form stable Zn(Ⅱ)-MACP-4 complexes both in solid state and solution with an association constant up to 5.97 (logKs). The molecular recognition of Zn(Ⅱ)-MACP-4 complexes towards various amino acids and anions with different geometry was investigated by using the spectral titration methods and X-ray analysis. The Zn(Ⅱ)-MACP-4 complex was found to recognize the 17 amino acids tested with the association constant up to 3.97 (logKs). On the other hand, the Zn(Ⅱ)-MACP-4 complex selectively interacted with anions and the maximum association constant of 3.9 (logKs) was obtained.