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Active Oxygen Radical Scavenging Ability of Water-Soluble β-Alanine C_(60) Adducts

Active Oxygen Radical Scavenging Ability of Water-Soluble β-Alanine C_(60) Adducts

作     者:Tao SUN Zhi Shen JIA Wei Xiang CHEN Ya Xu JIN Zhu De XU 

作者机构:Department of ChemistryZhejiang UniversityHangzhou 310027 

出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期:2001年第12卷第11期

页      面:997-1000页

核心收录:

学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基  金:教育部博士基金 

主  题:b-alanine C_(60) adducts superoxygen anion radical O_(2)^(.-) hydroxyl radical autoxidation of pyrogallol chemiluminescence. 

摘      要:Water-soluble b-alanine C60 adducts were synthesized, and the scavenging ability to superoxygen anion radical O2- and hydroxyl *** were studied by autoxidation of pyrogallol and chemiluminescence, respectively. It was found thatβ-alanine C60 adducts showed an excellent efficiency in eliminating superoxygen anion radical and hydroxyl radical. The 50% inhibition concentration (IC50) for superoxygen anion radical and hydroxyl radical were 0.15 mg/mL and 0.048 mg/mL, respectively. The difference should be mainly attributed to the different scavenging mechanisms.

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