Phototoxic effect of UVR on wild type, ebony and yellow mutants of Drosophila melanogaster: Life Span, fertility, courtship and biochemical aspects

作     者：WANG ZhePeng1,2, LIU RuiFang2, WANG AnRu3, DU LiLi1 & DENG XueMei1 1 College of Animal Science and Technology, China Agricultural University, Beijing 100094, China 2 Vocational and Technologic College, Inner Mongolia Agriculture University, Baotou 014109, China 3 College of Veterinary Medicine, China Agricultural University, Beijing 100094, China 

作者机构：College of Animal Science and Technology China Agricultural University Beijing 100094 China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2008年第51卷第10期

页      面：885-893页

核心收录：

学科分类：0710[理学-生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 09[农学] 

基　　金：the National Natural Science Foundati on of China(GrantNo.30471233) State Major Basic Research Developm ent Program of China (GrantNo.2006CB102100) 

主　　题：ultraviolet radiation Drosophila melanogaste free radicals pigment 

摘      要：Melanin plays an important role in protecting organisms from ultraviolet radiation (UVR). Therefore, it is possible that differently colored strains can show different sensitivities to UVR. In the present work, life span, fertility and courtship behavior of wild type (w), ebony (e) and yellow (y) strains of Drosophila melanogaster were studied to evaluate their sensitivity to ultraviolet (UV). Because a range of photo- toxic effects of UVR are mediated through generation of free radicals, levels of free radicals, lipid per- oxide (malondialdehyde, MDA) and superoxide dismutase (SOD) activity of three strains were examined to indicate their antioxidant defending ability and oxidative status. It was shown that w always had the highest lifespan and fertility not only in the control but also in UV-exposed groups. Moreover, lifespan and fertility of e were significantly higher (P0.05). MDA levels were increased in the UV dose-dependent manner (P=0.0495). In con- clusion, our results suggested that UVR can decrease life span and fertility of flies and do harm to courtship, which may be due to oxidative damage to flies tissues (e.g. central nervous system) induced by free radicals. w had the highest tolerance to UVR, which may be ascribed to its advantage of survival under the natural condition and at high level of SOD activity. Then differences of pigment between e and y in absorbing UV, shielding agai