Left ventricular reconstruction with no-patch technique：early and late clinical outcomes

作     者：HU Sheng-shou FAN Hong-guang ZHENG Zhe FENG Wei WANG Wei SONG Yun-hu WANG Li-qing YUAN Xin ZHANG Shi-ju 

作者机构：Department of Cardiovascular Surgery Research Center for Cardiovascular Regenerative Medicine Fu Wai Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Beijing 100037 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2010年第123卷第23期

页      面：3412-3416页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：The study was funded by Key Projects in the National Science & Technology Pillar Program during the Eleventh Five-year Plan Period (No. 2006BAI01A09) and Key Projects of Beijing Municipal Science & Technology Commission (No.D0906004040391) 

主　　题：left ventricular reconstruction no-patch technique follow-up clinical outcome 

摘      要：Background Few studies have evaluated late clinical outcome of no-patch technique in patients with large left ventricular aneurysms. The objectives of this study were to evaluate a no-patch surgical technique to reconstruct the left ventricle in patients with left ventricular aneurysm and to assess early and late clinical *** In 1995, we began using a no-patch technique in patients with dyskinetic left ventricular aneurysms. A total of 145 patients underwent left ventricular reconstruction with this technique and were followed up for （59±29） months （range,1-127 months）. Risk factors for early mortality were analyzed by bivariate analyses. Cox＇s proportional hazards model was used to calculate risk factors for all-cause mortality and hospital readmission. Kaplan-Meier methodology was used to analyze late *** One week after operation, left ventricular end-diastolic diameter had decreased from （61±8） mm to （55±8）mm, and geometry of the left ventricle was restored to a more normal conical shape. Early mortality was 3% and late mortality 11%. Over a 5-year follow-up period, hospital readmission was 28%. One-, 5-, and 10-year survival estimates were 95% （95% confidence interval （CI） 91%-99%）, 86% （95% CI 78%-94%）, and 74% （95% CI 60%-88%）.Readmission-free survival at 1 and 5 years after operation was 87% （95% CI81%-93%） and 60% （95% CI50%-70%）,*** The no-patch technique for left ventricular reconstruction is an effective and simple procedure that can achieve satisfactory early and late clinical outcomes in patients with left ventricular aneurysms.