Oxyphyllones A and B,novel sesquiterpenes with an unusual 4,5-secoeudesmane skeleton from Alpinia oxyphylla

作     者：Jun Ju Xu Ning Hua Tan Jiang Xiong Abiodun Humphrey Adebayo Hong Jin Han Guang Zhi Zeng Chang Jiu Ji Yu Mei Zhang Mei Ju Zhu 

作者机构：State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of Sciences Kunming 650204 PR China Department of Biological Sciences College of Science and Technology Covenant University Ota P.M.B. 1023 Ogun State Nigeria Graduate University of the Chinese Academy of Sciences Beijing 100049 PR China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2009年第20卷第8期

页      面：945-948页

核心收录：

学科分类：0710[理学-生物学] 071001[理学-植物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the grant from The National Natural Science Foundation of China(No.30725048) National Basic Research Program of China(No.2009CB522303) the Foundation of Chinese Academy of Sciences(West Light Program) 

主　　题：Alpinia oxyphylla Zingiberaceae 4,5-Secoeudesmane sesquiterpenoid Oxyphyllone A Oxyphyllone B 

摘      要：Two novel 4,5-secoeudesmane sesquiterpenoids, oxyphyllones A （1） and B （2） were isolated from the fruits of Alpinia oxyphylla. Their structures were established by spectroscopic methods including 1D and 21） NMR spectra. These two compounds are the first example of naturally occurring sesquiterpenoids with a 4,5-secoeudesmane skeleton in the family of Zingiberaceae and oxyphyllone A （1） is the first 4,5-secoeudesmane type of 13-norsesquiterpenoid. Compounds 1 and 2 exhibited no cytotoxicities against three cancer cell lines at 10 μg/mL. ？ 2009 Ning Hua Tan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.