Spontaneous regression of mantle cell lymphoma: a report of four cases
作者机构：Department of HematologyThe First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000ZhejiangP.R.China Department of Lymphoma/MyelomaThe University of Texas MD Anderson Cancer Center1515 Holcombe BlvdHoustonTX 77030USA The University of Texas Health Sci-ence CenterHoustonTX 77030USA Institute of Hematology and OncologyHarbin First HospitalHarbin 150000HeilongjiangP.R.China Department of HematologyDa Ping HospitalResearch Institute of SurgeryChongqing Third Military Medical UniversityChongqing 404100P.R.China
出 版 物：《Cancer Communications》 (癌症通讯（英文）)
年 卷 期：2018年第38卷第1期
页 面：329-334页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Mantle cell lymphoma Spontaneous regression
摘 要：Background:Spontaneous regression has been reported in some indolent forms of *** cell lym-phoma(MCL)is an aggressive lymphoid neoplasm and has a poor ***,approximately 30%of MCL patients can exhibit indolent clinical *** date,complete spontaneous regression of MCL has not been *** presentation:We describe four cases of spontaneous regression of *** the time of presentation,these patients were asymptomatic,with lymph node enlargement and mild to moderate fluorodeoxyglucose(FDG)uptake on FDG-positron emission tomography combined with computed *** of the possible mechanisms of spontaneous regression of the tumor could be due to the host immune response through humoral and cellular immunity,which may have a role in the clearance of tumor ***:In this report,we support the use of a“wait and watchstrategy for MCL patients with no risk factors and indolent *** strategy helps spare patients from further potentially harmful *** addition,we describe the phenomenon of spontaneous regression in MCL patients who are asymptomatic and have low-volume disease.
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