Effect of low-level laser therapy on tooth-related pain and somatosensory function evoked by orthodontic treatment

作     者：Song Wu Yinan Chen Jinglu Zhang Wenjing Chen Sheng Shao Huijie Shen Ling Zhu Ping Ye Peter Svensson Kelun Wang 

作者机构：Orofacial Pain and TMD Research UnitInstitute of StomatologyAffiliated Hospital of StomatologyNanjing Medical University136 Hanzhong RoadNanjingChina Institute of Stomatology and Department of OrthodonticsAffiliated Hospital of StomatologyNanjing Medical University136 Hanzhong RoadNanjingChina Department of StomatologyThe Children’s HospitalZhejiang University School of MedicineHangzhouChina Institute of Dental ResearchCentral for Oral HealthWestmead HospitalWestmeadAustralia Section of Orofacial Pain and Jaw FunctionDepartment of Dentistry and Oral HealthAarhus UniversityAarhusDenmark Department of Dental MedicineKarolinska InstitutetHuddingeSweden Scandinavian Center for Orofacial Neurosciences(SCON)StockholmSweden Center for Sensory-Motor Interaction(SMI)Department of Health Science and TechnologyAalborg UniversityAalborgDenmark 

出 版 物：《International Journal of Oral Science》 (国际口腔科学杂志（英文版）)

年 卷 期：2018年第10卷第3期

页      面：182-189页

核心收录：

学科分类：1003[医学-口腔医学] 10[医学] 

基　　金：funded by the Priority Academic Program Development of Jiangsu Higher Education Institution(Grant No.2014-37) the Jiangsu Provincial Health and Family Planning Commission(No.H201535) Orofacial Pain and TMD Research Unit,Institute of Stomatology,Affiliated Hospital of Stomatology,Nanjing Medical University,for their support 

主　　题：PG ANOVA Effect of low-level laser therapy on tooth-related pain and somatosensory function evoked by orthodontic treatment LG QST 

摘      要：Low-level laser therapy(LLLT) may have an effect on the pain associated with orthodontic treatment. The aim of this study was to evaluate the effect of LLLT on pain and somatosensory sensitization induced by orthodontic treatment. Forty individuals(12–33 years old; mean ± standard deviations: 20.8 ± 5.9 years) scheduled to receive orthodontic treatment were randomly divided into a laser group(LG) or a placebo group(PG)(1:1). The LG received LLLT(810-nm gallium-aluminium-arsenic diode laser in continuous mode with the power set at 400 mW, 2 J·cm–2) at 0 h, 2 h, 24 h, 4 d, and 7 d after treatment, and the PG received inactive treatment at the same time points. In both groups, the non-treated side served as a control. A numerical rating scale(NRS) of pain, pressure pain thresholds(PPTs), cold detection thresholds(CDTs), warmth detection thresholds(WDTs), cold pain thresholds(CPTs), and heat pain thresholds(HPTs) were tested on both sides at the gingiva and canine tooth and on the hand. The data were analysed by a repeated measures analysis of variance(ANOVA). The NRS pain scores were significantly lower in the LG group(P = 0.01). The CDTs,CPTs, WDTs, HPTs, and PPTs at the gingiva and the PPTs at the canine tooth were significantly less sensitive on the treatment side of the LG compared with that of the PG(P 0.033). The parameters tested also showed significantly less sensitivity on the nontreatment side of the LG compared to that of the PG(P 0.043). There were no differences between the groups for any quantitative sensory testing(QST) measures of the hand. The application of LLLT appears to reduce the pain and sensitivity of the tooth and gingiva associated with orthodontic treatment and may have contralateral effects within the trigeminal system but no generalized QST effects. Thus, the present study indicated a significant analgesia effect of LLLT application during orthodontic *** clinical applications are suggested.