Essential oils as alternatives to antibiotics in swine production

作     者：Faith A.Omonijo Liju Ni Joshua Gong Qi Wang Ludovic Lahaye Chengbo Yang 

作者机构：Department of Animal ScienceUniversity of Manitoba Shanghai Lab-Animal Research Center Guelph Food Research CentreAgriculture and Agri-Food Canada Jefo Nutrition Inc. 

出 版 物：《Animal Nutrition》 (动物营养（英文版）)

年 卷 期：2018年第4卷第2期

页      面：126-136页

核心收录：

学科分类：090502[农学-动物营养与饲料科学] 0905[农学-畜牧学] 09[农学] 

基　　金：supported by Natural Sciences and Engineering Council of Canada (NSERC) (CRDPJ 503580-16) Collaborative Research and Development Grants (C.Yang) the University of Manitoba Start-Up Grant (46561) Manitoba Pork Council (47370) Jefo Nutrition Inc (47369) 

主　　题：Essential oils Organic acids Medium chain fatty acids Inflammation Oxidative stress Pigs 

摘      要：This review article summarizes the efficacy, feasibility and potential mechanisms of the application of essential oils as antibiotic alternatives in swine *** there are numerous studies demonstrating that essential oils have several properties, such as antimicrobial, antioxidative and antiinflammatory effects, feed palatability enhancement and improvement in gut growth and health, there is still a need of further investigations to elucidate the mechanisms underlying their *** the past,the results has been inconsistent in both laboratory and field studies because of the varied product compositions, dosages, purities and growing stages and conditions of *** minimal inhibitory concentration(MIC) of essential oils needed for killing enteric pathogens may not ensure the optimal feed intake and the essential oils inclusion cost may be too high in swine *** the lipophilic and volatile nature of essential oils, there is a challenge in effective delivery of essential oils within pig gut and this challenge can partially be resolved by microencapsulation and *** effects of essential oils on inflammation, oxidative stress, microbiome, gut chemosensing and bacterial quorum sensing(QS) have led to better production performance of animals fed essential oils in a number of *** has been demonstrated that essential oils have good potential as antibiotic alternatives in feeds for swine *** combination of different essential oils and other compounds(synergistic effect) such as organic acids seems to be a promising approach to improve the efficacy and safety of essential oils in ***-throughput systems technologies have been developed recently,which will allow us to dissect the mechanisms underlying the functions of essential oils and facilitate the use of essential oils in swine production.