Wide-field in situ multiplexed Raman imaging with superresolution

作     者：HOUKAI CHEN XIAOJING WU YUQUAN ZHANG YONG YANG CHANGJUN MIN SIWEI ZHU XIAOCONG YUAN QIAOLIANG BAO JING BU 

作者机构：Nanophotonics Research Center Shenzhen Key Laboratory of Micro-Scale Optical Information Technology Shenzhen UniversityShenzhen 518060 China Tianjin Union Medical Center Tianjin 300121 China Institute of Modern Optics Nankai University Tianjin 300071 China College of Electronic Science and Technology Shenzhen UniversituyShenzhen 518060 China 

出 版 物：《Photonics Research》 (光子学研究（英文版）)

年 卷 期：2018年第6卷第6期

页      面：530-534页

核心收录：

学科分类：080901[工学-物理电子学] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 

基　　金：National Natural Science Foundation of China(NSFC)(61490712,61427819,91750205,61605117) National Key Basic Research Program of China(973)(2015CB352004) Leading Talents of Guangdong Province Program(00201505) Natural Science Foundation of Guangdong Province(2016A030312010,2016A030310063,2017A030313351) National Key Research and Development Program of China(2016YFC0102401) Science and Technology Innovation Commission of Shenzhen(KQTD2017033011044403,KQTD2015071016560101,ZDSYS201703031605029) Excellent Young Teacher Program of Guangdong Province(YQ2014151) 

主　　题：Raman microscopy Surface-enhanced Raman scattering Superresolution 

摘      要：Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surface- enhanced Raman scattering （SERS） technique, wide-field Raman imaging is developed with a significant improve- ment in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-fidd multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.