Comparison of Enhancement Effect of DNA-Mediated Energy Transfer by Divalent Cations： Mg2＋, Ca2＋, Mn2＋, Co2＋, and Ni2＋

作     者：Jong-Moon Kim Myung Duk Jang JIN Biao Yoon Jung Jang 

作者机构：Department of Health Care and BiotechnologyKyungwoon UniversityGumi CityGyeong-buk 730-739Republic of Korea Materials & Energy Engineering College of IT & EnergyKyungwoon UniversityGumi CityGyeong-buk 730-739Republic of Korea Instrumental 

出 版 物：《光谱学与光谱分析》 (Spectroscopy and Spectral Analysis)

年 卷 期：2018年第38卷第6期

页      面：1970-1974页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 0804[工学-仪器科学与技术] 070302[理学-分析化学] 0703[理学-化学] 0702[理学-物理学] 

基　　金：the National Research Foundation of Korea(20011-0013534,2009-0076930) the National Natural Science Foundation of China(21265022) 

主　　题：光学 文摘 英文 

摘      要：The effect of various metal ions on the DNA mediated energy transfer between simultaneously bound drugs was investigated using spectroscopic *** was found that addition of divalent metal ions(Mg^(2+),Ca^(2+),Mn^(2+),Co^(2+)and Ni^(2+))resulted in further decrease of the ethidium fluorescence intensity,while a small increase was observed in the TMPyP emission band,implying that the energy of excited ethidium was transferred to *** DNA-mediated quenching efficiency between ethidium and TMPyP was significantly enhanced by the presence of all metal *** the divalent metal ions,alkali earth metal ions and Mn^(2+)displayed higher quenching efficiencies than other transition metal *** distances required to permit the energy transfer between the two drugs in DNA were calculated as 68,66,62,48and 38in the presence of100μmol·L^(-1 )of Mg^(2+),Ca^(2+),Mn^(2+),Co^(2+)and Ni ^(2+)ion,*** disturbed binding conformation of TMPyP in DNA by metal ions presumably accounts for the difference.