补锌对12～18月龄儿童智力和精神运动评分的影响:一个随机双盲试验
Impact of zinc supplementation on mental and psychomotor scores of children aged 12 to 18 months: A randomized, double- blind trial作者机构：Department of Pediatrics All India Inst. of Medical Sciences NewDelhi 110029 India Dr.
出 版 物：《世界核心医学期刊文摘（儿科学分册）》 (Dkgest of the World Latest Medical Information)
年 卷 期：2005年第1卷第8期
页 面：34-34页
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100404[医学-儿少卫生与妇幼保健学] 10[医学]
主 题：儿童智力 随机双盲 补锌 运动评分 年龄别身高 身高别体重 发育量表 安慰剂对照 智力发育指数 锌元素
摘 要：Objective: To evaluate the effect of zinc supplementation on mental and psych omotor scores in children aged 12 to 18 months. Study design: In this double- b lind, randomized, placebo- controlled trial, children aged 6 to 30 months recei ved daily elemental zinc (10 mg for infants and 20 mg for others) or placebo for 4 months. Bayley Scales of Infant Development II were used for development asse ssment in the 12- to 18- month subgroup at enrollment and the end of the study . Results: At the end of the study, the adjusted mean mental (P = .36) and psych omotor (P = .28) index scores were similar in the intervention and control group s. In a multivariate model, the baseline mental development index score was posi tively associated with the mother’s schooling, the child’s height for age, p acked cell volumes, hospital birth, and attendance at a day care center, and was negatively associated with the child’s age. Breastfeeding, the child’s weig ht for height, and packed cell volumes were positively associated with the basel ine psychomotor index score. Conclusion: Zinc supplementation did not affect the mental or psychomotor development index scores in a setting in which zinc defic iency is common.
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