“Applause征”有助于将PSP与FTD和PD相鉴别

作     者：Dubois B. Slachevsky A. Pillon B. 张琪 

作者机构：INSERM U 610 Pavill on Claude Bernard H.opital de la Salêtrière 47 Bd. de l’ Hpital 7501 3 Paris France Dr. 

出 版 物：《世界核心医学期刊文摘（神经病学分册）》 (Digest of the World Core Medical Journals:Clinical Neurology)

年 卷 期：2005年第1卷第10期

页      面：56-57页

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：进行性核上麻痹 额颞叶痴呆 帕金森病 Applause FTD PD PSP 纹状体 鉴别率 变性疾病 

摘      要：The “ applause sign is a simple test of motor control that helps to diffe rentiate PSP from frontal or striatofrontal degenerative diseases. It was found in 0/39 controls, 0 of 24 patients with frontotemporal dementia (FTD), 0 of 17 p atients with Parkinson disease (PD), and 30/42 patients with progressive supranu clear palsy (PSP). It discriminated PSP from FTD (p 0.001) and PD (p 0.00). The “ three clap test correctly identified 81.8% of the patients in the co mparison PSP and FTD and 75% of the patients in the comparison of PSP and PD.