Lower tacrolimus trough levels in the late period after living donorliver transplantation contribute to improvements in long-term clinicaloutcomes

作     者：lei geng li-dong wang jun-jie huang tian shen zhuo-yi wang bing-yi lin yu-fu ye shu-sen zheng 

作者机构：Division of Hepatobiliary and Pancreatic SurgeryDepartment of SurgeryThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Key Laboratory of Combined Multi-organ TransplantationMinistry of Public HealthKey Laboratory of Organ TransplantationHangzhou 310003China Key Laboratory of Organ TransplantationHangzhou 310003China Collaborative Innovation Center for Diagnosis Treatment of Infectious DiseasesHangzhou 310003China 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2018年第17卷第3期

页      面：204-209页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by grants from Zhejiang Provincial Natural Science Foundation(LQ15H030003 and LY18H030002) the Public Welfare Project of Zhejiang Province(2016C37025) the Fundamental Research Funds for the Central Universities(2017FZA7009) 

主　　题：Liver transplantation Complications Immunosuppression 

摘      要：Background： Previous studies have emphasized the need to reduce tacrolimus （TAC） trough levels in theearly post-liver transplantation （LT） period. However, whether late-period TAC trough levels influence the long-term outcomes of liver recipients is not clear.