Concise synthesis of xanthones by the tandem etherification——Acylation of diaryliodonium salts with salicylates

作     者：Gaoxiaozheng Liu Chao Wu Bifeng Chen Ru He Chao Chen 

作者机构：MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology Department of Chemistry Tsinghua University The Graduate School at Shenzhen Tsinghua University 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2018年第29卷第6期

页      面：985-988页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China (Nos. 21372138 and 21672120) The National Key Research and Development Program of China (No. 2016YFB0401400) the Fok Ying Tong Education Foundation of China (No. 151014) the Postdoctoral Foundation of the PekingTsinghua Joint Center for Life Sciences 

主　　题：Xanthone Diaryliodonium salts Etherification Acylaion Multiple substituent 

摘      要：An efficient synthetic method for multi-substituted xanthones was developed. The reaction of diaryliodonium salts and salicylates was employed for the preparation of the xanthones. This method proceeded through an intermolecular etherification-acylation to give target heterocycles in good yields（up to 91%）. Multi-substituted xanthones were gained by shifting the substituent of salicylates or diaryliodonium salts