ROLE OF RESTING SYSTOLIC LOADING CONDITIONS IN DETERMINING LEFT VENTRICULAR FUNCTIONAL RESERVE IN CHRONIC AORTIC REGURGITATION

作     者：沈卫峰 龚兰生 Peter J. Fletcher Gary S. Roubin Phillip J. Harris David T. Kelly 

作者机构：Ruijin Hospital Shanghai Second Medical University Shanghai Hallstrom Institute of Cardiology University of Sydney Sydney Australia 

出 版 物：《中华医学杂志(英文版)》 (Chinese Medical Journal)

年 卷 期：1987年第100卷第7期

页      面：527-534页

核心收录：

学科分类：1002[医学-临床医学] 

摘      要：The relationship between systolic loading condi-tions at rest and left ventricular （LV） functional response to exercise was assessed in 31 patients with aortic regurgitation （AR） and 10 controls. The peak and end systolic wall stress determined from echocar-diography and cuff systolic pressure at rest were used as indirect measures of LV systolic loading, and compared with LV ejection fraction response to handgrip and bicycle exercise by radionuclide ven-trieulography. Both peak and end systolic wall stress were significantly higber in asymptomatic （164±33 and 90±25×10～3 dynes/cm2） and symptomatic （196±33 and 134±17×10～3 dynes/cm2） patients with AR than in the controls （125±22 and 61±14×10～3 dynes cm2, p0.01）, and correlated in-versely with the changes in LV ejection fraction during handgrip （r=-0.63 and r=-0.73） and bicycle （r=0.68 and r=-0.87） *** patients with AR, resting systolic loading conditions appear to reflect LV functional reserve during exercise.