Diagnostic value of whole-body MRI with diffusion-weighted sequence for detection of peritoneal metastases in colorectal malignancy

作     者：Huan Zhang Weixing Dai Caixia Fu Xu Yan Alto Stemmer Tong Tong Guoxiang Cai 

作者机构：Department of RadiologyFudan University Shanghai Cancer CenterDepartment of OncologyShanghai Medical CollegeFudan UniversityShanghai 200032China Department of Colorectal SurgeryFudan University Shanghai Cancer CenterDepartment of OncologyShanghai Medical CollegeFudan UniversityShanghai 200032China Siemens Shenzhen Magnetic Resonance LtdShenzhen 518000China MR ColLaboration NE AsiaSiemens HealthcareShanghai 210318China MR Applications DevelopmentSiemens HealthcareErlangen 91052Germany 

出 版 物：《Cancer Biology & Medicine》 (癌症生物学与医学（英文版）)

年 卷 期：2018年第15卷第2期

页      面：165-170页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(Grant No.81501437) the Shanghai Municipal Planning Commission of Science and Research Fund(Grant No.JGGG1401) 

主　　题：MRI diffusion-weighted imaging peritoneal cancer index peritoneal metastases colorectal malignancy 

摘      要：Objective：To assess the diagnostic accuracy of whole-body MRI using diffusion-weighted sequence（WB-DWI）to determine the peritoneal cancer index（PCI）in correlation with surgical and histopathological ***：Twenty-seven patients underwent preoperative WB-MRI,followed by cytoreductive surgery for primary tumors of the appendix（n=15）,colorectum（n=12）,and associated peritoneal disease.A total of 351 regions were retrospectively *** sensitivity,specificity,and accuracy were calculated at 13 anatomical *** WB-DWI PCI and PCI type were compared with surgical and histopathological ***：No statistical difference was found between the WB-DWI PCI and surgical PCI（P=0.574）.WB-DWI correctly predicted the PCI type in 24 of 27 patients with high accuracy（88.9%）,including 10 of 10 patients with small-volume tumor,12 of 14 with moderate-volume tumor,and 2 of 3 with large-volume ***-DWI correctly depicted tumors in 163 of 203 regions,with 40false-negative and 23 false-positive *** overall sensitivity,specificity,and accuracy of WB-DWI for the detection of peritoneal tumors were 80.3%,84.5%,and 82.1%,*** lesions＆lt;0.5 cm in diameter,WB-DWI demonstrated good sensitivity（69.4%）.Conclusions：WB-DWI accurately predicted PCI before surgery in patients undergoing evaluation for cytoreductive surgery.