New insights into the helical structure of 30-nm chromatin fibers

作     者：Ping Chen Ping Zhu Guohong Li 

作者机构：National Laboratory of Biomacromolecules Institute of Biophysics Chinese Academy of Sciences 

出 版 物：《Protein & Cell》 (蛋白质与细胞(英文))

年 卷 期：2014年第5卷第7期

页      面：489-491页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

基　　金：supported by grants from the National Basic Research Program (973 Program) (Nos. 2011CB966300 to G.L., 2010CB912400 and 2009CB825500 to P.Z.) the National Natural Science Foundation of China (Grant Nos. 91219202, 91019007 to G.L., 31230018, 21261130090 to P.Z. and 31000566 to P.C.) Strategic Priority Research Program (XDA01010304 to G.L., XDB08010100 to P.Z.) Key Research Program (KJZD-EW-L05 to P.Z. and G.L.) from the Chinese Academy of Sciences the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry to P.C 

主　　题：chromatin ray/neutron centrifugation 

摘      要：In eukaryotic cells, genomic DNA is highly packaged into chromatin to fit inside the nucleus. The accessibility of DNA is dependent on the packing density of chromatin fibers,which plays a critical role in transcriptional regulation and all other DNA-related biological processes.