ERYTHROCYTE MEMBRANE LIPID COMPOSITION FLUIDITY IN PATIENTS WITH ESSENTIAL HYPERTENSION

作     者：符云峰 董玉枝 李红 卢振敏 王薇 

作者机构：Department of Biochemistry Hebei Academy of Medical Sciences Shijiazhuang. 

出 版 物：《中华医学杂志(英文版)》 (Chinese Medical Journal)

年 卷 期：1992年第105卷第10期

页      面：803-808页

核心收录：

学科分类：10[医学] 

主　　题：TRANSPORT 

摘      要：The lipid composition and fluidity of erythrocyemembrane in 36 patients with essential hypertensionwere *** results showed that eithercholesterol/phospholipid molar ratio or lipid perox-ides content was significantly increased(P0.01 or0.001),and the superoxide dismutase activity,contentsof four classes of phospholipids,i.e.,phosphotidylethanolamine,phosphotidylcholine,phosphotidylserineand sphingomyelin of erythrocyte membrane,and lipidfluidity were significantly decreased(P0.05,0.01or0.001)as compared with those in 35 normotensivecontrol *** results suggested that thechanges of lipid composition and fluidity might associ-ate with the decreased activities of cation transportsystems in cell membranes and play an important rolein the pathogenesis of essential hypertension.