Recent progress in copper catalyzed asymmetric Henry reaction

作     者：Sheng Zhang Yanan Li Youguo Xu Zhiyong Wang 

作者机构：Hefei National Laboratory for Physical Sciences at Microscale CAS Key Laboratory of Soft Matter Chemistry & Collaborative Innovation Center of SuzhouNano Science and Technology Department of Chemistry University of Science and Technology of China College of Chemistry and Pharmaceutical Engineering Nanyang Normal University 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2018年第29卷第6期

页      面：873-883页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the National Natural Science Foundation of China (Nos. 2127222, 21432009, 21472177, J1310010) Chinese Academy of Sciences(No. XDB20000000) 

主　　题：Henry reaction Asymmetric catalysis Copper catalysis Nitro compounds C-C bond formation 

摘      要：Henry reaction is one of the most classical reactions to construct synthetically useful product nitro alcohol, which as a privileged skeleton is widely distributed in various pharmaceuticals. This review summarizes the recent progress of copper-catalyzed asymmetric Henry reaction from 2011 to 2016. The significant progress that has been made in this area will be highlighted and some of challenges that the author believes may be hindering further progress will be revealed.