Enhanced Adhesion of Mussel-inspired Adhesive through Manipulating Contents of Dopamine Methacrylamide and Molecular Weight of Polymer

作     者：Xiong Xiong Yumei Liu Feng Shi Guowei Zhang Jie Weng Shuxin Qu 

作者机构：Key Lab of Advanced Technologies of Materials Ministry of Education School of Materials Science and Engineering Southwest Jiaotong University Chengdu 610031 China School of Life Science and Engineering Southwest Jiaotong University Chengdu 610031 China College of Environmental Science and Engineering China West Normal University Nanchong 637009 China Collaboration Innovation Center for Tissue Repair Material Engineering Technology China West Normal University Nanehong 637009 China 

出 版 物：《Journal of Bionic Engineering》 (仿生工程学报（英文版）)

年 卷 期：2018年第15卷第3期

页      面：461-470页

核心收录：

学科分类：081704[工学-应用化学] 082903[工学-林产化学加工工程] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 0829[工学-林业工程] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：This study is supported by National Basic Research Program of China (973 Program  2012CB933602)  National Natural Science Foundation of China (Grant No. 51372210)  Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20130184110023)  the Basic Research Foundation Key Project of Sichuan Province (Grant No. 2016JY0011)  The Fundamental Research Funds for the Central Universities (Grant No. 2682016YXZT11)  and Basic Research Foundation of Leshan (2017) 

主　　题：mussel-inspired adhesive adhesion dopamine methacrylamide 

摘      要：The aim of this study is to investigate the effect of the contents of modified 3, 4-dihydroxyphenyl-L-alanine （DOPA）, named as do- pamine methacrylamide （DMA）, on the adhesion of mussel-inspired adhesives in air and water. A series of adhesives, p（DMA-co-MEA）, were synthesized by copolymerized DMA and methoxy ethylacrylate （MEA） with the content of DMA from 2 mol.% to 10 mol.%. Results of IH NMR show that the contents of DMA in all adhesives are near to the theory ratios of DMA in the staring reagents. Adhesives with more than 5 mol.% of DMA appear adhesion, while adhesives with 2 mol. % and 3 mol. % of DMA show almost no adhesion in air and water. Adhesive with 7 mol.% of DMA has the highest molecular weight and adhesion either in air or in water in all adhesives. Adhesion of adhesive is synergistically influenced by the content of DMA, molecular weight and elastic modulus of adhesive. It is because that higher content of DMA would provide more DOPA, which leads to the coordination bond between DOPA and metal ions. It is feasible to develop the mussel-inspired adhesive through incorporating DMA into polymers, which will have potential application in the clinic.