Experimental study of diode-laser induced thermocoagulation on hepatic tissue with scanner fiber tip
Experimental study of diode-laser induced thermocoagulation on hepatic tissue with scanner fiber tip作者机构：DepartmentofGeneralSurgerySirRunRunShawHospitalZhejiangUniversityHangzhou310016ZhejiangProvinceChina DepartmentofPathologyMedicalCollegeofZhejiangUniversityHangzhou310006ZhejiangProvinceChina DepartmentofPhysicsStateKeyLaboratoryofSiliconMarterialZhejiangUniversityHangzhou310027ZhejiangProvinceChina
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2003年第9卷第10期
页 面：2350-2352页
核心收录：
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1002[医学-临床医学] 08[工学] 100214[医学-肿瘤学] 10[医学]
基 金：the Youth Science Foundation of National 863 Laser Technique
摘 要：AIM: To explore a safe, efficient, and cost-effective technique for local thermo-ablation of hepatic ***: The livers of 16 healthy rabbits were thermocoagulated by diode-laser with a hand-made scanner fiber tip, 6 w for 10 min. At the same time, the temperature was measured at 5 and 10 mm from the laser tip. Liver function 7 days post-thermocoagulation was compared to pre-thermocoagulation. Pathological changes were also studied 1 month after laser ***: All the rabbits lived and the temperature of hepatic tissues at 0 mm, 5 mm, 10 mm from laser tip reached 96.39±3.97 ℃, 60.79±6.21℃, 46.10±4.58 ℃, respectively after 10 min thermocoagulation. There was no significant change in liver function. The hepatic thermocoagulated necrosis and the surrounding fibrosis was 26.0 mm in diameter. Light microscopy observation revealed no surviving cells in the coagulated ***: Hepatic tissue can be locally ablated safely and effectively by diode-laser with scanner fiber tip, and this technique may be a new method to treat hepatic tumors.
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