STUDIES ON PERIPHERAL T LYMPHOCYTE SUBSETS IN PATIENTS WITH AUTOIMMUNE THYROID DISEASES

作     者：Chen Gong Zhang Kai-zhen Liao Zeng-hua Wang Su-he Ma Shu-jun Long Zhen-zhou Tian Wei-tao Zhu Ji-yu 

作者机构：Fujian Medical College Fuzhou Department of Microbiology and Immunology Beijing Medical University Beijing 

出 版 物：《中华医学杂志(英文版)》 (Chinese Medical Journal)

年 卷 期：1989年第102卷第9期

页      面：701-701页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

摘      要：Peripheral T lymphocyte subsets in 60 cases of Graves disease (GD) and 16 cases of Hashimoto’s thyroiditis (HT) were determined by the use of OKT monoclonal antibodies (McAb). The results showed that in both diseases OKT3 cells (total T cells ) and OKT8 cells (suppressor T cells, TS cells) were lower and the ratio of LKT4 cells (helper T cells, TH cells)/OKT8 cells was much higher than those in normal controls. GD patients who were treated with antithyroid drugs (ATD) and whose serum T3, T4 recovered to normal, could be further divided into subgroups of high OKT4/OKT8 cell ratio and of normal ratio. The pathogenesis, treatment and relapse of autoimmune thyroid diseases (AITD) were discussed in this paper on the basis of the results.