THE EFFECTS OF ZINC ON THE ALVEOLAR MACROPHAGE CYTOTOXICITY DUE TO NI-COAL DUST
作者机构:Institute of Industrial Health and Occupational Diseases Zhejiang Academy of Medical Sciences Hangzhou.
出 版 物:《中华医学杂志(英文版)》 (Chinese Medical Journal)
年 卷 期:1990年第103卷第9期
页 面:754-758页
核心收录:
学科分类:12[管理学] 1201[管理学-管理科学与工程(可授管理学、工学学位)] 08[工学]
摘 要:The possibility of the combined effects on the alveolar macrophage cytotoxicity due to zine and Ni-coal dust was studied. The parameters in the experiments were cellular ATP level in alveolar macrophage (AM), cellular Kand Znin AM and the surface morphological changes of AM. The experimental results showed that low zinc can protect the toxicity of Ni-coal dust on AM, and that the protective effects on the toxicity of Ni-coal dust by zinc are dependent on its dosage. The ATP level and Kcontent in AM are sensitive indices in reflecting the cytotoxicity and can be used in detecting environmental toxic substances.