Koninginins N-Q, Polyketides from the Endophytic Fungus Trichoderma koningiopsis Harbored in Panax notoginseng

作     者：Kai Liu Ya-Bin Yang Jin-Lian Chen Cui-Ping Miao Qiang Wang Hao Zhou You-Wei Chen Yi-Qing Li Zhong-Tao Ding Li-Xing Zhao 

作者机构：Yunnan Institute of MicrobiologySchool of Life ScienceYunnan UniversityKunming 650091People’s Republic of China 

出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)

年 卷 期：2016年第6卷第1期

页      面：49-55页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：This work was supported partly by grants from the National Natural Science Foundation of China(Nos.81360480 21262041 and 81460536) 

主　　题：Trichoderma koningiopsis Polyketide Antifungal activity Bioactivity assay Koninginin 

摘      要：Four new fungal polyketides named koninginins N-Q(1–4),together with four known analogues(5–8),were isolated from the endophytic fungus Trichoderma koningiopsis YIM PH30002 harbored in Panax *** structures were determined on the basis of spectral data *** compounds were evaluated for their antifungal activity,nitric oxide inhibition,and anticoagulant activity.