三角形小管发是一种内毛根鞘角化缺陷病:1例张力细丝结构异常的超微结构观察报道
Pili trianguli et canaliculi is a defect of inner root sheath keratinization: Ultrastructural observations of anomalous tonofilament organization in a case作者机构：Dr.Department of Dermatology Mayo Clinic 200 First Street SW Rochester MN 55905 United States
出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)
年 卷 期：2005年第1卷第8期
页 面：47-47页
学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学]
主 题：毛根鞘 小管 角化 超微结构观察 超微结构改变 表面特征 继发性改变 附着点 毛干 细胞骨架
摘 要：A 4- year- old Caucasian girl with pili trianguli et canaliculi had distinctive findings. These included unique ultrastructural alterations consisting of tonofilament- desmosomal detachment and tonofilament clumping within inner root sheath cells. We believe that the hair anomaly in this condition may be due to a compromised cytoskeleton with subsequent configurational changes of the inner root sheath. Despite these configurational changes keratinization of the inner root sheath occurs. As inner root sheath keratinization typically precedes keratinization of the hair shaft, the abnormally configured inner root sheath determines the surface characteristics of the hair shaft in pili trianguli et canaliculi.
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