儿童甲状腺炎及其他自身免疫性疾病与白癜风的相关性研究
Relevance of thyroiditis and of other autoimmune diseases in children with vitiligo作者机构：Phototherapy Unit San Gallicano Institute IRCCS Via Elio Chianesi 53 IT-00144 Roma Italy
出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)
年 卷 期：2005年第1卷第5期
页 面：28-28页
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
主 题：儿童甲状腺炎 自身免疫性疾病 甲状腺疾病 甲状腺功能不全 儿科患者 甲状腺自身抗体
摘 要：Background:Studies that clearly define the possible association of childhood vitiligo with autoimmune and/or endocrine diseases are lacking. Objective:To ex amine the presence of autoimmune disorders, in particular of thyroid disease, in paediatric patients with vitiligo and investigate the utility of such screening in these patients. Methods:One hundred and twenty-one paediatric patients (40 males, 81 females) with vitiligo were grouped in segmental and non-segmental v itiligo. All patients were screened for thyroid disease. Results:13 out of 121 patients had different degrees of thyroid parameter alterations. These patients were all affected by the non-segmental type while none of those with the segmen tal form presented thyroid alterations. Conclusion:In paediatric patients with non-segmental vitiligo, a significant incidence of thyroid dysfunction was foun d. Since vitiligo usually appears before the development of the thyroid disease, it may be useful to screen thyroid autoantibodies in all paediatric patients wi th non-segmental vitiligo who present symptoms related to thyroid disease.
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