Chemoselective synthesis of novel aminoindolizines using aminopyridines, acetylenic diesters and α-halo ketones

作     者：Sakineh Asghari Mohammad Qandalee Vahideh Behboodi Arastoo Nouri Gorji Ghasem Firouzzade Pash 

作者机构：Department of Organic ChemistryFaculty of ChemistryUniversity of Mazandaran Nano and Biotechnology Research GroupUniversity of Mazandaran Department of BiologyGarmsar BranchIslamic Azad University 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2016年第27卷第3期

页      面：361-364页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the Research Council of the University of Mazandaran Iran 

主　　题：Aminopyridines a Halo ketones Acetylenic diesters Indolizine Chemoselective synthesis 

摘      要：A chemoselective synthesis of novel indolizine derivatives were reported via three-component reactions of aminopyridines, acetylenic diesters and a-halo ketones. In these reactions, the zwitterion generated from aminopyridines and acetylenic diesters reacted with a-halo ketones to produce indolizine skeleton in good to high yields under mild reaction conditions.