Focusing on the Focus： What Else beYOnd the Master Switches for Polar Cell Growth？

作     者：Yuan Qin Juan Dong 

作者机构：Center for Genomics and Biotechnology College of Crop Science Fujian Agriculture and Forestry University Fuzhou 350002 Fujian Province China Waksman Institute of Microbo ogy Rutgers the State University of New Jersey Piscataway NJ 08854 LISA The Department of Plant Biology and Pathology Burgers the State University of New Jersey New Brunswick NJ 08901 USA 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2015年第8卷第4期

页      面：582-594页

核心收录：

学科分类：0710[理学-生物学] 090601[农学-基础兽医学] 07[理学] 09[农学] 0906[农学-兽医学] 071007[理学-遗传学] 0901[农学-作物学] 0902[农学-园艺学] 090102[农学-作物遗传育种] 

基　　金：Y.Q. is supported by the Ministry of Science and Technology of China (2011CB944603 2012C8944801), National Natural Science Foundation of China (31170290 31470284), and Program for New Century Excellent Talents in Fujian Province University (JA14096). J.D. is supported by grants front the U.S. National Institute of General Medical Sciences (R01GM 109080) and Rutgers University. ACKNOWLEDGMENTS We apologize for the work not cited in tills review due to the size Iirnit. No conflict of interest declared, 

主　　题：cell expansion cytoskeleton polarity polarity determination signal transduction 

摘      要：Cell polarity, often associated with polarized cell expansion/growth in plants, describes the uneven distribution of cellular components, such as proteins, nucleic acids, signaling molecules, vesicles, cytoskeletal elements, and organelles, which may ultimately modulate cell shape, structure, and function. Pollen tubes and root hairs are model cell systems for studying the molecular mechanisms underlying sustained tip growth. The formation of intercalated epidermal pavement cells requires excitatory and inhibitory pathways to coordinate cell expansion within single cells and between cells in contact. Strictly controlled cell expansion is linked to asymmetric cell division in zygotes and stomatal lineages, which require integrated processes of pre-mitotic cellular polarization and division asymmetry. While small GTPase ROPs are recognized as fundamental signaling switches for cell polarity in various cellular and developmental processes in plants, the broader molecular machinery underpinning polarity establishment required for asymmetric division remains largely unknown. Here, we review the widely used ROP signaling pathways in cell polar growth and the recently discovered feedback loops with auxin signaling and PIN effluxers. We discuss the conserved phosphorylation and phospholipid signaling mechanisms for regulating uneven distribution of proteins, as well as the potential roles of novel proteins and MAPKs in the polarity establishment related to asymmetric cell division in plants.