Eu(Ⅲ) Indirect Probe to Investigate Interaction of DOPA (3,4,Di-Hydroxyphenylalanine) and Dopamine (3,4-Dihydroxy Phenyl Ethyl Amine) Using Electrochemical Methods

作     者：Prashant N Bhatt Trupti V Pathak Jignasu P Mehta G.Ramchandraiha 

作者机构：Department of ChemistryBhavnagar University Bhavnagar-364002 India Central Salt and Marine Chemical Research Institute Waghavadi RoadBhavnagar-364002India 

出 版 物：《Journal of Rare Earths》 (稀土学报（英文版）)

年 卷 期：2006年第24卷第6期

页      面：653-658页

核心收录：

学科分类：0709[理学-地质学] 0819[工学-矿业工程] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 0708[理学-地球物理学] 070302[理学-分析化学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Foundation ite m:Project supported by DST(SP/S1/F03/98) 

主　　题：electrochemistry of Eu ( Ⅲ ) chrono techniques electrochemistry of Eu ( Ⅲ )-neurotransmitters solutionstudy rare earths 

摘      要：Eu（ Ⅲ ） can be utilized as an indirect electrochemical probe to investigate the interaction of bio-molecules such as DOPA and Dopamine with Ca（ Ⅱ ） in vitro. The interaction of DOPA and Dopamine with Eu（ Ⅲ ）-Eu（ Ⅱ ） redox pair was investigated by electrochemical techniques. Both the neurotransmitters are structurally related and undergo interaction with Eu （Ⅲ ）. Eu （ Ⅲ ） coordinates with DOPA and Dopamine through five-member chelate tings via carboxylic oxygen and amino nitrogen. The electrode kinetic parameters viz, transfer coefficient （αna）, diffusion coefficient （D）, forward heterogeneous rate constant （ k^0 fh） were evaluated for Eu（ Ⅲ ）-DOPA/Eu（ Ⅲ ）-Dopamine. The results obtained were used to investigate the nature of interaction of Eu （Ⅲ） with muhi-donor biomolecules. The possible mechanism was also proposed.