Effect of Shengmaisan(生脉散)on Lipid Peroxidation Damage in Acute Myocardial infarctionPatients
Effect of Shengmaisan (生脉散) on Lipid Peroxidation Damage inAcute Myocardial infarction Patients出 版 物:《Chinese Journal of Integrative Medicine》 (中国结合医学杂志(英文版))
年 卷 期:1996年第2卷第4期
页 面:249-251页
学科分类:1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
主 题:Shengmaisan acute myocardial infarction free radical lipid peroxidation
摘 要:The effect of Shengmaisan (SMS) on coronary heart disease (CHD) patients, 30 anginapectoris and 68 acute myocardial infarction (AMI) and its peroxidation damage was studied. It was shownthat the activities of superoxide dismutase (SOD) and glutathione peroxidase ( GSH-Px) in blood decreasedand the content of malondialdehyde (MDA) in plasma increased in CHD patients in comparison with thehealthy controls (P 0. 05 ) . It could be assumed that the pathogenesis of CHD is associated withfree radical (FR) triggering a chain reaction of the lipid peroxidation, and that SMS is acting as an effectivefree radical scavenger, which would ameliorate the lipid peroxidation damage . Thus, SMS could be adminis-tered in the prevention and the treatment of CHD.