Regulation of neuroinflammatory properties of glial cells by T cell effector molecules

作     者：chittappen k.prajeeth jochen huehn martin stangel 

作者机构：clinical neuroimmunology and neurochemistrydepartment of neurologyhannover medical schoolHannoverGermany experimental immunologyhelmholtz centre for infection researchBraunschweigGermany center of systems neurosciencehannover medical schoolGermany 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2018年第13卷第2期

页      面：234-236页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学] 

基　　金：supported by the Helmholtz-Gemeinschaft,“Zukunft-sthema”Immunology and inflammation”(ZT-0027) supported by the Pertermax-Müller-Stiftung and the Niedersachsen Research Network on Neuroinfectiology(N-RENNT)of the Ministry of Science and Culture of Lower Saxony 

主　　题：Regulation of neuroinflammatory properties of glial cells by T cell effector molecules Th CNS 

摘      要：Multiple sclerosis （MS） is a chronic inflammatory and neurodegenerative disorder that is thought to be mediated by autoreactive T lymphocytes that find their way into the central nervous system （CNS）. The pathological mechanism of MS is still being elucidated but it involves complex interactions between infiltrating immune cells and resi- dent glial cells within the CNS that culminate into strong neuroinflammation and axonal damage.