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Adenosine A2A-dopamine D2 receptor heteromers operate striatal function:impact on Parkinson's disease pharmacotherapeutics

Adenosine A_(2A)-dopamine D_2 receptor heteromers operate striatal function: impact on Parkinson's disease pharmacotherapeutics

作     者:víctor fernández-duenas sergi ferré francisco ciruela 

作者机构:unitat de farmacologiadepartament patologia i terapèutica experimentalfacultat de medicinaidibelluniversitat de barcelonal’hospitalet de llobregatBarcelonaSpain institut de neurociènciesuniversitat de barcelonaBarcelonaSpain integrative neurobiology sectionnational institute on drug abuseintramural research programnational institutes of healthBaltimoreMDUSA 

出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))

年 卷 期:2018年第13卷第2期

页      面:241-243页

核心收录:

学科分类:0710[理学-生物学] 07[理学] 08[工学] 071006[理学-神经生物学] 081201[工学-计算机系统结构] 0812[工学-计算机科学与技术(可授工学、理学学位)] 

基  金:supported by MINECO/ISCⅢ(SAF2014-55700-P and PIE14/00034) IWT(SBO-140028) Fundacióla Maratóde TV3(Grant 20152031)to FC FC and VFD belong to the“Neuropharmacology and Pain”accredited research group(Generalitat de Catalunya,2014 SGR 1251) the intramural funds of the National Institute on Drug Abuse to SF 

主  题:A(2A) RECEPTORS BASAL GANGLIA DOPAMINE-D-2 

摘      要:The basal ganglia (BG) assemble a series of deep gray matter structures forming recurrent loops that include the cortex and thalamus, and that participate in the regulation of a plethora of brain functions, including elicitation and learning of reward-and aversive stimuli-associated behaviors, motor activity control and sensorimotor gating (Brom- berg-Martin et al., 2010).

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