Potential Role of EGF and EGFR in Tongue Coating Formation

作     者：Yi-Shuang Tang Yu-Feng Mao Yu Zhao Jing-Hua Peng Yi-Yang Hu 

作者机构：Institute of Liver Diseases Shuguang Hospital Shanghai University of Traditional Chinese Medicine Shanghai 201203 China Shanghai Key Laboratory of Traditional Chinese Clinical Medicine Key Laboratory of Liver and Kidney Diseases Ministry of EducationShanghai 201203 China 

出 版 物：《World Journal of Traditional Chinese Medicine》 (世界中医药杂志（英文）)

年 卷 期：2016年第2卷第4期

页      面：62-69页

学科分类：100505[医学-中医诊断学] 1005[医学-中医学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China Shanghai Educational Development Foundation[14CG41] 

主　　题：Tongue coating epidermal growth factor epidermal growth factor receptor review 

摘      要：Tongue coating, as a sensitive index of the physiological and pathological changes of human organs, is an important basis for the Traditional Chinese Medicine(TCM) syndrome differentiation and treatment. Mechanism of the formation and change of tongue coating is an important scientific problem. In recent years, researches indicated that in addition to apoptosis related genes, epidermal growth factor(EGF) and epidermal growth factor receptor(EGFR) also contribute to tongue coating formation. In this paper, we summarized recent studies on the potential role of EGF and EGFR in regulating the formation of tongue coating to provide some reference for the further investigations on tongue coating formation mechanisms.