Progress of Research on Organic Fibrosis with Traditional Chinese Medicine

作     者：Qing-Lan Wang Xiao-Ning Wang Ping Liu 

作者机构：E-Institute of Shanghai Municipal Education Committee Shanghai University of Traditional Chinese Medicine Institute of Liver Diseases Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine 

出 版 物：《World Journal of Traditional Chinese Medicine》 (世界中医药杂志（英文）)

年 卷 期：2016年第2卷第2期

页      面：53-59页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by National Natural Science Foundation of China (81573873, 81273728, 8153000502, 81270053, 81573810) China Postdoctoral Science Foundation (2015T80445) Natural Science Foundation of Shanghai, China (14ZR1441400) E-institutes of Shanghai Municipal Education Commission, China (E03008) 

主　　题：Organic fibrosis traditional Chinese medicine(TCM) clinical efficacy Fuzheng Huayu recipe 

摘      要：Fibrosis is the remodeling and repair processes of chronic injuries. There are few effective therapies. Chinese medicine formula, the main pattern of traditional Chinese medicine(TCM) in clinic, applies a multi-component, multi-target and complicated approach in the treatment of diseases, and certainly shows good comprehensive therapeutic effects on fibrosis. In this review, the clinical study, effects and mechanism of action of Fuzheng Huayu recipe in the treatment of liver, pulmonary, and renal fibrosis was analyzed and evaluated. Meanwhile, based on the understanding of TCM pathogenesis for liver cirrhosis, this review will also briefly introduce the research of different classical Chinese medicine formulae with various functions in the treatment of experimental liver fibrosis induced by different methods, including comparing the efficacy, analyzing the action characteristics and mechanism of effective formulae, exploring pathological and biological basis of TCM diagnostic and therapeutic pattern, which will contribute to the research of TCM in the treatment of organ fibrosis.