Total Synthesis and Biological Evaluation of Wewakazole
Total Synthesis and Biological Evaluation of Wewakazole作者机构：The Fourth People's Hospital ofShenzhen Shenzhen 518033 P. R. China Shenzhen Institute of Geriatncs Shenzhen 518020 P. R. China The Second People's Hospital of Shenzhen Shenzhen 518035 P. R. China Key Lab for New Drug Research of TCM and Shenzhen Branch State R&D Centre for Viro-Biotech Research Institute of Tsinghua University in Shenzhen Shenzhen 518057 P. R. China
出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)
年 卷 期：2017年第33卷第6期
页 面：890-894页
核心收录：
基 金：the Health and Family Planning Commission of Shenzhen Municipality, China the Basic Research Project of Shenzhen Science and Technology Plan, China
主 题：Wewakazole Total synthesis Biological evaluation
摘 要：The total synthesis of Wewakazole was achieved on a gram scale, unambiguously confirming its structure. Three different substituted oxazoles present in this natural product were prepared efficiently. Biological evaluation indicated that Wewakazole significantly inhibited cancer cell proliferation in a dose-dependent manner.
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