An expression atlas of miRNAs in Arabidopsis thaliana

作     者：Le Xu Yugang Hu Ying Cao Jingrui Li Ligeng Ma Yan Li Yijun Qi 

作者机构：Center for Plant Biology School of Life Sciences Tsinghua University Beijing 100084 China Tsinghua-Peking Center for Life Sciences Beijing 100084 China College of Biologieal Sciences China Agricultural University Beijing 100094 China College of Life Sciences-Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement Capital Normal University Beijing 100048 China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2018年第61卷第2期

页      面：178-189页

核心收录：

学科分类：0710[理学-生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

基　　金：supported by grants fromNational Key Research and Development Program of China (2016YFA0500800) National Natural Science Foundation of China (31421001, 31225015) to Yijun Qi 

主　　题：Arabidopsis miRNAs 地图集 生物过程 织物类型 生命周期 表示模 非编码 

摘      要：MicroRNAs(miRNAs) are small non-coding RNAs that regulate a variety of biological processes. miRNA expression often exhibits spatial and temporal specificity. However, genome-wide miRNA expression patterns in different organs during development of Arabidopsis thaliana have not yet been systemically investigated. In this study, we sequenced small RNA libraries generated from 27 different organ/tissue types, which cover the entire life cycle of Arabidopsis. Analysis of the sequencing data revealed that most miRNAs are ubiquitously expressed, whereas a small set of miRNAs display highly specific expression patterns. In addition, different miRNA members within the same family have distinct spatial and temporal expression patterns. Moreover, we found that some miRNAs are produced from different arms of their hairpin precursors at different developmental stages. This work provides new insights into the regulation of miRNA biogenesis and a rich resource for future investigation of miRNA functions in Arabidopsis.