Research on human glioma stem cells in China

作     者：Yao-dong Zhao Quan-bin Zhang Hua Chen Xi-feng Fei Yun-tian Shen Xiao-yan Ji Jia-wei Ma Ai-dong Wang Jun Dong Qing Lan Qiang Huang 

作者机构：Department of Neurosurgery and Brain Tumor Research LaboratorySecond Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Shanghai General HospitalShanghaiChina Shanghai 10th People's HospitalShanghaiChina Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Suzhou Kowloon HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2017年第12卷第11期

页      面：1918-1926页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China No.81172400 81101909 81272793 81302180 81302196 81472739 

主　　题：nerve regeneration glioma stem cells China cell culture molecular characteristics cellular origin cell function microenvironment molecular targeted therapy chemotherapy radiotherapy neural regeneration 

摘      要：Research on human glioma stem cells began early in the 21st century and since then has become a rapidly growing research field with the number of publications increasing year by year. The research conducted by our diverse group of investigators focused primarily on cell culture techniques, molecular regulation, signaling pathways, cancer treatment, the stem cell microenvironment and the cellular origin and function of glioma stem cells. In particular, we put forward our view that there are inverse or forward transformations among neural stem cells, glial cells and glioma stem cells in glioma tissues under certain conditions. Based on the background of the progress of international research on human glioma stem cells, we aim to share our progress and current findings of human glioma stem cell research in China with colleagues around the world.