冷冻治疗早产儿视网膜病变10年后的视力研究:早产儿视网膜病变残余物的影响

作     者：Dobson V. Quinn G. E. Summers C. G. 王大江(译) 

作者机构：不详 DepartmentofOphthalmology UniversityofArizona 655 N Alvernon Tucson AZ 85711 United States 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2006年第2卷第6期

页      面：21-22页

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100212[医学-眼科学] 10[医学] 

主　　题：早产儿视网膜病变 视力检查 残余物 冷冻治疗 10年后 糖尿病视网膜病变 早期治疗 视力损害 ROP 眼科医师 

摘      要：Objective: To describe recognition (letter) acuity at age 10 years in eyes with and without retinal residua of retinopathy of prematurity (ROP). Design: Presence and severity of ROP residua were documented by a study ophthalmologist. Masked testers measured monocular recognition visual acuity (Early Treatment of Diabetic Retinopathy Study) when the children were 10 years old. Two hundred forty-seven of 255 surviving Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) randomized trial patients participated. A reference group of 102 of 104 Philadelphia-based CRYO-ROP study participants who did not develop ROP was also tested. Results: More severe retinal residua were associated with worse visual acuity,regardless of whether retinal ablation was performed to treat the severe acute-phase ROP. However,within each ROP residua category,there was a wide range of visual acuity results. Conclusions: This is the first report of the relation between visual acuity (Early Treatment of Diabetic Retinopathy Study charts) and structural abnormalities related to ROP in a large group of eyes that developed threshold ROP in the perinatal period. Visual deficits are greater in eyes with more severe retinal residua than in eyes with mild or no residua. However,severity of ROP residua does not predict the visual acuity of an individual eye because within a single residua category,acuity may range from near normal to blind.