Impacts of energy feeds and supplemental protease on growth performance, nutrient digestibility, and gut health of pigs from 18 to 45 kg body weight

作     者：Hongyu Chen Shihai Zhang Inkyung Park Sung Woo Kim 

作者机构：Department of Animal ScienceNorth Carolina State University 

出 版 物：《Animal Nutrition》 (动物营养（英文版）)

年 卷 期：2017年第3卷第4期

页      面：359-365页

核心收录：

学科分类：0710[理学-生物学] 090502[农学-动物营养与饲料科学] 0905[农学-畜牧学] 0906[农学-兽医学] 09[农学] 

基　　金：awarded from United Sorghum Checkoff Program(Lubbock  TX  USA) 

主　　题：Growth performance Gut health Pigs Protease Sorghum 

摘      要：A total of 144 pigs with 18.4 ± 2.3 kg initial body weight(BW) at 6 wk of age were used in a 40-d trial to evaluate effects of protease(300,000 U/kg feed, BioResource International Inc., Durham, NC, USA) on growth performance, apparent ileal digestibility(AID) of nutrients, and gut health of pigs fed diets with sorghum. Pigs were randomly allotted to 4 treatments(12 pens per treatment, 3 pigs per pen) in a 2 x 2 factorial arrangement(corn or sorghum basal diets, and 0 or 0.05% protease as 2 factors) with sex and initial BW as blocks. Experimental period had phase 1(d 1 to 21) and phase 2(d 22 to 40). About 65%(phase 1) and 72%(phase 2) of cereal grains were used in corn or sorghum based diets. Both grains were ground to 400 μm. Body weight and feed intake were recorded weekly. On d 35, serum was collected to quantify tumor necrosis factor-a(TNF-a) and malondialdehyde(MDA). Titanium dioxide(0.3%) was added as an indigestible marker for an additional 4 d feeding. On d 40, 32 pigs(8 pigs per treatment)were euthanized to collect digesta from jejunum and ileum(for viscosity and AID), tissues(for morphology) and mucosa samples(for TNF-α and MDA) from duodenum, jejunum, and ileum. Replacing corn with sorghum in the diet increased(P 0.05) overall average daily gain(from 756 to 787 g/day) and average daily feed intake(from 1,374 to 1,473 g/day), reduced(P 0.05) overall gain:feed ratio(from0.553 to 0.537), and did not affect AID. Pigs fed diets with sorghum had lower(P 0.05) MDA content in serum(from 14.61 to 6.48 μmol/L) and jejunum(from 1.42 to 0.91 μmol/g protein), and reduced(P 0.05) villus height(from 492 to 396 μm) and crypt depth(from 310 to 257 μm) in jejunum. Dietary protease improved(P 0.05) AID of crude protein(from 81.8% to 86.0%), decreased MDA level(from 1.20 to 0.98 μmol/g protein) in duodenum, and increased(P 0.05) the ratio of villus height to crypt depth(from 1.08 to 1.21) in duodenum. Overall, use of sorghum fully replacing corn in diets could b