Paving the road for biomedicine: genome editing and stem cells in primates

作     者：Yuyu Niu Tianqing Li Weizhi Ji 

作者机构：Yunnan Key Laboratory of Primate Biomedicine Research Institute of Primate Translational Medicine Kunming University of Science and Technology 

出 版 物：《National Science Review》 (国家科学评论(英文版))

年 卷 期：2017年第4卷第4期

页      面：543-549页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：supported by the National Key Research and Development Program of China(2016YFA0101401) the National Natural Science Foundation of China(U1302227 and U1602224) 

主　　题：genome editing stem cells non-human primate 

摘      要：Non-human primates(NHPs) are similar with humans in their anatomy, physiology, genetics and neural functions, and in their cognition, emotions and social behavior. The NHP model has played an important role in the biomedical research, development of vaccines and drugs and new therapies for many *** advances in genome editing have generated NHP models for human diseases. Genome editing integrated with derivation of NHP pluripotent stem cells now provides an optimal resource to regenerate medicine.