Saponins and solvent extracts from Atriplex laciniata L. exhibited high anthelmintic and insecticidal activities

作     者：Zul Kamal Farhat Ullah Sajjad Ahmad Muhammad Ayaz Abdul Sadiq Muhammad Imran Shujat Ahmad Faiz Ur Rahman Anwar Zeb 

作者机构：Department of Pharmacy Shaheed Benazir Bhutto University Sheringal Dir Upper 18050Pakistan Department of Pharmacy University of Malakand Chakdara Dir Lower 18000 Pakistan Department of Zoology Shaheed Benazir Bhutto University Sheringal Dir Upper 18050 Pakistan 

出 版 物：《Journal of Traditional Chinese Medicine》 (中医杂志（英文版）)

年 卷 期：2017年第37卷第5期

页      面：599-606页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 1005[医学-中医学] 1002[医学-临床医学] 100602[医学-中西医结合临床] 10[医学] 

主　　题：Saponins Atriplex 寄生虫 Heterotermes indicola Monomorium pharaonis Rhyzopertha dominica Tribolium castaneum 

摘      要：OBJECTIVE: To investigate saponins and various solvent extracts from Atriplex laciniata(A. laciniata)against human parasites and various ***: The samples from A. laciniata used in the activities were crude saponins(*** F) and solvent samples including methanolic extract(*** F), ethyl acetate(*** F), choloroform(*** F),n-hexane(*** F) and water residual(*** F). Anthelmintic potentials of the samples were analyzed against Pheretima posthuma(earthworms) and Ascaridia galli(round worms) using contact toxicity method. Insecticidal activities were performed against Heterotermes indicola(termite), Monomorium pharaonis(pharaoh ant), Tribolium castaneum(flour beetle) and Rhyzopertha dominica(grain borer) using standard ***: In anthelmintic assay, *** F and *** F were most effective against P. posthuma and A. gal-li with average death times of 25.62 and 29.65 min respectively. Likewise the anthelmintic assay, *** F and *** F were most effective against H. indicola causing 90.36% and 73.24% lethality respectively. Furthermore, in anti-Pharaoh activity *** F, *** F, *** F, *** F and *** F exhibited highest activity with LD50 of 78, 220, 260, 330 and 800 mg/m L respectively. *** F and *** F were highly effective against R. dominica causing 80.11% and71.30% lethality respectively. *** F was found most active against T. ***: Our findings suggest that the *** F, *** F and *** F extracted from *** *** be the best options for the isolation of anthelmintic and bio-insecticidal compounds.