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RNA methylation regulates hematopoietic stem and progenitor cell development

RNA methylation regulates hematopoietic stem and progenitor cell development

作     者:Jason Ear Shuo Lin 

作者机构:Department of Molecular Cell and Developmental Biology University of California Los Angeles 90095 CA USA 

出 版 物:《Journal of Genetics and Genomics》 (遗传学报(英文版))

年 卷 期:2017年第44卷第10期

页      面:473-474页

核心收录:

学科分类:0710[理学-生物学] 07[理学] 071009[理学-细胞生物学] 09[农学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

主  题:RNA methylation regulates hematopoietic stem and progenitor cell development 

摘      要:Methylation of adenosine base on the nitrogen-6 position (N6-methyladenosine, m^6A) is the most common and abundant modification on mRNA transcripts. This post-transcriptional modification was first described in the 1970s in hepatoma cells (Desrosiers et al., 1974).

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